Structure of PDB 4aik Chain A Binding Site BS01

Receptor Information
>4aik Chain A (length=139) Species: 633 (Yersinia pseudotuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STLGSDLARLVRVWRALIDHRLKPLELTQTHWVTLYNINRLPPEQSQIQL
AKAIGIEQPSLVRTLDQLEEKGLITRHTSANDRRAKRIKLTEQSSPIIEQ
VDGVISSTRKEILGGISSDEIAVLSGLIDKLEKNIIQLQ
Ligand information
Receptor-Ligand Complex Structure
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PDB4aik Structural Basis for Intrinsic Thermosensing by the Master Virulence Regulator Rova of Yersinia.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		Q49 Q60 V64 R78 R86 K88
Binding residue
(residue number reindexed from 1)		Q47 Q58 V62 R76 R84 K86
Binding affinityPDBbind-CN: Kd=46nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0001216 DNA-binding transcription activator activity
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006950 response to stress
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0032993 protein-DNA complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4aik, PDBe:4aik, PDBj:4aik
PDBsum4aik
PubMed22936808
UniProtB1JJ73|SLYA_YERPY Transcriptional regulator SlyA (Gene Name=slyA)

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