Structure of PDB 4aen Chain A Binding Site BS01

Receptor Information
>4aen Chain A (length=178) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4aen Peptide Linkage to the Alpha-Subunit of Mhcii Creates a Stably Inverted Antigen Presentation Complex.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		Q9 F22 R50 F51 A52 S53 F54 G58 A59 N62 V65 A68 N69 I72 M73
Binding residue
(residue number reindexed from 1)		Q7 F20 R48 F49 A50 S51 F52 G56 A57 N60 V63 A66 N67 I70 M71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4aen, PDBe:4aen, PDBj:4aen
PDBsum4aen
PubMed22820093
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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