Structure of PDB 4a76 Chain A Binding Site BS01

Receptor Information
>4a76 Chain A (length=86) Species: 8364 (Xenopus tropicalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQVLRGSGHCKWFNVRMGFGFISMTSREGSPLENPVDVFVHQSKLYMEGF
RSLKEGEPVEFTFKKSSKGFESLRVTGPGGNPCLGN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4a76 The Lin28 Cold-Shock Domain Remodels Pre-Let-7 Microrna.
Resolution1.92 Å
Binding residue
(original residue number in PDB)		W39 N41 V42 M44 G45 F46 F48 D64 F66 H68 Q69 F77 R78 S93 K95 E98
Binding residue
(residue number reindexed from 1)		W12 N14 V15 M17 G18 F19 F21 D37 F39 H41 Q42 F50 R51 S66 K68 E71
Binding affinityPDBbind-CN: Kd=59nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:4a76, PDBe:4a76, PDBj:4a76
PDBsum4a76
PubMed22570413
UniProtB4F6I0

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