Structure of PDB 4a36 Chain A Binding Site BS01

Receptor Information
>4a36 Chain A (length=523) Species: 8839 (Anas platyrhynchos) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKARSYQIELAQPAINGKNALICAPTGSGKTFVSILICEHHFQNMPAGRK
AKVVFLATKVPVYEQQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIED
SDIIVVTPQILVNSFEDGTLTSLSIFTLMIFDECHNTTGNHPYNVLMTRY
LEQKFNSASQLPQILGLTASVGVGNAKNIEETIEHICSLCSYLDIQAIST
VRENIQELQRFMNKPEIDVRLVKRRIHNPFAAIISNLMSETEALMRTIFG
TQNYEHWIVVTQRKCREEESRICRALFICTEHLRKYNDALIISEDARIID
ALSYLTEFFTNVKNGPYTELEQHLTAKFQEKEPELIALSKDETNENPKLE
ELVCILDDAYRYNPQTRTLLFAKTRALVSALKKCMEENPILNYIKPGVLM
GRGMTLPSQKGVLDAFKTSKDNRLLIATSVADEGIDIVQCNLVVLYEYSG
NVTKMIQVRGRGRAAGSKCILVTSKTEVVENEKCNRYKEEMMNKAVEKIQ
KWDEETFAKKIHNLQMKERVLRD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4a36 Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		G382 N383 H384 Q508 N509
Binding residue
(residue number reindexed from 1)		G139 N140 H141 Q252 N253
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:4a36, PDBe:4a36, PDBj:4a36
PDBsum4a36
PubMed22000019
UniProtD3TI84

[Back to BioLiP]