Structure of PDB 3ztt Chain A Binding Site BS01

Receptor Information
>3ztt Chain A (length=278) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSE
ADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVIYLEGQN
EKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLD
KLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEG
TPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDS
IAEQGKEGDSYYSMMKYNLDKIAEGLAK
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain3ztt Chain A Residue 1000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3ztt A molecular mechanism for bacterial susceptibility to zinc.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H67 H139 E205 N226 D280
Binding residue
(residue number reindexed from 1)		H36 H108 E174 N195 D249
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0007155 cell adhesion
GO:0030001 metal ion transport

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3ztt, PDBe:3ztt, PDBj:3ztt
PDBsum3ztt
PubMed22072971
UniProtP0A4G2|MTSA_STRPN Manganese ABC transporter substrate-binding lipoprotein PsaA (Gene Name=psaA)

[Back to BioLiP]