Structure of PDB 3zp5 Chain A Binding Site BS01

Receptor Information
>3zp5 Chain A (length=92) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEVARRWGERKSK
PNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRFDFQGLAQAC
Ligand information
Receptor-Ligand Complex Structure
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PDB3zp5 Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
Q48 L49 W87 K91 M96 K100 Y108
Binding residue
(residue number reindexed from 1)
Q5 L6 W44 K48 M53 K57 Y65
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:3zp5, PDBe:3zp5, PDBj:3zp5
PDBsum3zp5
PubMed25866208
UniProtQ99581|FEV_HUMAN Protein FEV (Gene Name=FEV)

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