Structure of PDB 3zkc Chain A Binding Site BS01

Receptor Information
>3zkc Chain A (length=61) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IGQRIKQYRKEKGYSLSELAEKAGVAKSYLSSIERNLQTNPSIQFLEKVS
AVLDVSVHTLL
Ligand information
Receptor-Ligand Complex Structure
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PDB3zkc Molecular Basis of the Activity of Sinr, the Master Regulator of Biofilm Formation in Bacillus Subtilis.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
A27 S29 Y30 Q39 N41 P42 S43
Binding residue
(residue number reindexed from 1)
A26 S28 Y29 Q38 N40 P41 S42
Binding affinityPDBbind-CN: Kd=360nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0010629 negative regulation of gene expression
GO:0030435 sporulation resulting in formation of a cellular spore
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:3zkc, PDBe:3zkc, PDBj:3zkc
PDBsum3zkc
PubMed23430750
UniProtP06533|SINR_BACSU HTH-type transcriptional regulator SinR (Gene Name=sinR)

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