Structure of PDB 3zk4 Chain A Binding Site BS01

Receptor Information

>3zk4 Chain A (length=569) Species: 3873 (Lupinus luteus)

HAYIKATPNVLGFEGHYTEWVTLQYSNNKPSIDDWIGVFSPANFSASTCP
GENKMTNPPFLCSAPIKFQYANFSSHSYKDTGKGSLKLQLINQRSDFSFA
LFTGGLTNPKLIAVSNKVSFVNPNAPVYPRLAQGKTWDEITVTWTSGYDI
NDAEPFVEWGPKEGNLVKTPAGTLTFDRNTMCGAPARTVGWRDPGYIHTS
FLKELWPNREYTYKLGHRLFNGTTIWSKEYHFKASPYPGQSSVQRVVIFG
DMGKAEADGSNEYNNFQPGSLNTTKQIIQDLEDIDIVFHIGDLCYANGYI
SQWDQFTAQIEPIASTVPYMTASGNHERDWPGTGSFYGNLDSGGECGVPA
QTMFFVPAENREKFWYSTDYGMFRFCIAHTELDWRKGTEQYEFIEKCLAS
VDRQKQPWLIFLAHRVLGYSSAGFYVQEGSFEEPMGREDLQHLWQKYKVD
IAMYGHVHNYERTCPIYQNVCTNKEKHNYKGNLNGTIHVVVGGGGASLAE
FAPINTTWSIFKDHDFGFVKLTAFDHSNLLLEYRKSSDGQVYDSFTISRD
YRDILACSVDSCPTTTLAS

Ligand information

• Ligand ID: FE
• InChI: InChI=1S/Fe/q+3
• InChIKey: VTLYFUHAOXGGBS-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [Fe+3]
• Formula: Fe
• Name: FE (III) ION
• DrugBank: DB13949
• PDB chain: 3zk4 Chain A Residue 800

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3zk4 The Structure of a Purple Acid Phosphatase Involved in Plant Growth and Pathogen Defence Exhibits a Novel Immunoglobulin-Like Fold
• Resolution: 1.65 Å
• Binding residue (original residue number in PDB): D272 D313 Y316 H479
• Binding residue (residue number reindexed from 1): D251 D292 Y295 H458
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): D272 D313 Y316 N346 H347 H435 F445 Y446 H477 H479
• Catalytic site (residue number reindexed from 1): D251 D292 Y295 N325 H326 H414 F424 Y425 H456 H458
• Enzyme Commision number: 3.1.3.2: acid phosphatase.

Gene Ontology

Molecular Function

• GO:0003993 acid phosphatase activity
• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:3zk4, PDBe:3zk4, PDBj:3zk4
• PDBsum: 3zk4
• PubMed: 25075326
• UniProt: Q8VX11