Structure of PDB 3zfc Chain A Binding Site BS01

Receptor Information
>3zfc Chain A (length=337) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKGIPVRVALRCRPLVSKEIKEGCQTCLSFVPGEPQVVVGNDKSFTYDFV
FDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTA
EQEHDSAIGVIPRVIQLLFKEINKKSDFEFTLKVSYLEIYNEEILDLLCS
QINIREDPKEGIKIVGLTEKTVLVASDTVSCLEQGNNSRTVASTAMNSQS
SRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLRE
GININRGLLCLGNVISALGDDKKGNFVPYRDSKLTRLLQDSLGGNSHTLM
IACVSPADSNLEETLNTLRYADRARKIKNKPIINHHH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3zfc Chain A Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3zfc Structural Basis for the ATP-Induced Isomerization of Kinesin.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		T95 S211
Binding residue
(residue number reindexed from 1)		T91 S201
Annotation score4
Enzymatic activity
Enzyme Commision number 3.6.4.4: Transferred entry: 5.6.1.3.
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:3zfc, PDBe:3zfc, PDBj:3zfc
PDBsum3zfc
PubMed23500491
UniProtP33174|KIF4_MOUSE Chromosome-associated kinesin KIF4 (Gene Name=Kif4)

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