Structure of PDB 3zev Chain A Binding Site BS01

Receptor Information
>3zev Chain A (length=307) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PNSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSTVD
YYLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACT
YATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIP
MLFTMGLQNLSGDGTHPGGLVCTPIVDTATLKVVIQVNTFMSFLFPMLVA
SILNTVIANKLTVMVHQPGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRL
MFCYISDEQWTTFLFDFYHYFYMLTNALVYVSAAINPILYNLVSANFRQV
FLSTLAC
Ligand information
Receptor-Ligand Complex Structure
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PDB3zev Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Resolution3.0 Å
Binding residue
(original residue number in PDB)		D54 L55 D56 Y146 V224 T226 R327 F331 C332 I334 D336 W339 F344 Y347
Binding residue
(residue number reindexed from 1)		D4 L5 D6 Y93 V171 T173 R248 F252 C253 I255 D257 W260 F265 Y268
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0016492 G protein-coupled neurotensin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3zev, PDBe:3zev, PDBj:3zev
PDBsum3zev
PubMed24453215
UniProtP20789|NTR1_RAT Neurotensin receptor type 1 (Gene Name=Ntsr1)

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