Structure of PDB 3zbp Chain A Binding Site BS01

Receptor Information
>3zbp Chain A (length=301) Species: 169683 (Phikzvirus phiKZ) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVKTRIYFCGGAGFRIGELFHGYHEDVCYIDTSVQNKHKHNTDDNTIIIE
ADTKQTARKRAIGMGKDRKAAAELISAHIPAIAHHFPAGDTNIVVYSMGG
ASGSTIGPSLVSHLQQQGEVVVSVVIGSYDSDISLRNSSGSLKTFEGVSS
VSKVPMIINYHENVEGIPQSMVNQNILEVLNALVILFNQEHQSLDLMDIT
NWAHFHKHHDVPVQTVQLHVCFDRQEAQAILDPISIASLYTDPDRDVSIS
TVLTRTTGYADPEKYDFDQMHFVINGLSIEDIRKRLEERREMMNRAKANM
R
Ligand information
Ligand IDGDP
InChIInChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKeyQGWNDRXFNXRZMB-UUOKFMHZSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6c1nc2c(n1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
CACTVS 3.385NC1=Nc2n(cnc2C(=O)N1)[C@@H]3O[C@H](CO[P](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
CACTVS 3.385NC1=Nc2n(cnc2C(=O)N1)[CH]3O[CH](CO[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 12.01O=P(O)(O)OP(=O)(O)OCC3OC(n2cnc1c2N=C(N)NC1=O)C(O)C3O
OpenEye OEToolkits 1.7.6c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
FormulaC10 H15 N5 O11 P2
NameGUANOSINE-5'-DIPHOSPHATE
ChEMBLCHEMBL384759
DrugBankDB04315
ZINCZINC000008215481
PDB chain3zbp Chain A Residue 999 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3zbp Structure of the Tubulin/Ftsz-Like Protein Tubz from Pseudomonas Bacteriophage Phikz
Resolution2.0 Å
Binding residue
(original residue number in PDB)		G13 G14 A15 R18 K72 S103 G106 A107 S108 I132 S134 D136 N169 Q175 V178 N179
Binding residue
(residue number reindexed from 1)		G10 G11 A12 R15 K66 S97 G100 A101 S102 I126 S128 D130 N163 Q169 V172 N173
Annotation score4
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0016787 hydrolase activity
Cellular Component
GO:0030430 host cell cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3zbp, PDBe:3zbp, PDBj:3zbp
PDBsum3zbp
PubMed23528827
UniProtQ8SDC3|PHUZ_BPDPK Phage tubulin-like protein (Gene Name=PHIKZ039)

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