Structure of PDB 3x2x Chain A Binding Site BS01

Receptor Information
>3x2x Chain A (length=227) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GMKVTFLGHAVVLIEGKKNIIIDPFISGNPVCPVKLEGLPKIDYILVTAG
HGDHLGDAVEIAKKNDATVISNYEICHYLGKKGVKTHAMHIGGSYLFDFG
RVKMTPAVHGSGILDGDSMIYGGNPSGFLITIEGKKIYHAGDTGLTREME
LLAEENVDVAFLPIGGNFVMDVEDAVRAAVMIKPKKVVPMHYGTWELIFA
DVELFKKKVEEKGVECVILEPGESLEL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain3x2x Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3x2x Crystal structure of metallo-beta-lactamase H48A from Thermotoga maritima
Resolution3.42 Å
Binding residue
(original residue number in PDB)		H50 D52
Binding residue
(residue number reindexed from 1)		H51 D53
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:3x2x, PDBe:3x2x, PDBj:3x2x
PDBsum3x2x
PubMed
UniProtQ9X0P5|Y1162_THEMA UPF0173 metal-dependent hydrolase TM_1162 (Gene Name=TM_1162)

[Back to BioLiP]