Structure of PDB 3x1l Chain A Binding Site BS01

Receptor Information

>3x1l Chain A (length=573) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPE
HVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEE
IKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFT
VSITWVSLSEKEDIYQVTENAGLSRVLERIAIYPLLVKILDSLGERKVTE
ERFEKSEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIK
RYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVS
EDFVKDNMLVDSDLYYSSTWESEEKVKEVVDFLNAAYKEIGNPPKYYAIL
VMDGDTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVD
KALEVAYKIRKEFGKSFKLSAGILIVHYKHPLYDALEKARDLLNNKAKNV
PGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLEGKRFIYHVL
REVDTWPKVGIDEMLKFEVIRHIRNKEETKELREKIYGEIKDLLEHVRGN
NEVEKVRGLFTFLKIITDAEVFP

Ligand information

>3x1l Chain J (length=22) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ccgcaaggaccgcatactacaa

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3x1l Crystal structure of the CRISPR-Cas RNA silencing Cmr complex bound to a target analog.
Resolution	2.096 Å
Binding residue (original residue number in PDB)	E555 R790
Binding residue (residue number reindexed from 1)	E321 R494

Enzymatic activity

Catalytic site (original residue number in PDB)	F264 I270
Catalytic site (residue number reindexed from 1)	F47 I53
Enzyme Commision number	?

External links

PDB	RCSB:3x1l, PDBe:3x1l, PDBj:3x1l
PDBsum	3x1l
PubMed	25921071
UniProt	Q8U1S6\|CMR2_PYRFU CRISPR system Cmr subunit Cmr2 (Gene Name=cmr2)

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