Structure of PDB 3x14 Chain A Binding Site BS01
Receptor Information
>3x14 Chain A (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIFKTNTQTDRESLRILLRYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>3x14 Chain C (length=9) Species:
10377
(Human herpesvirus 4 strain B95-8) [
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FLRGRAYGL
Receptor-Ligand Complex Structure
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PDB
3x14
The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
Y7 D9 F22 F36 Y59 N63 I66 N70 T73 D74 S77 Y84 S97 Y99 N114 T143 K146 W147 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 D9 F22 F36 Y59 N63 I66 N70 T73 D74 S77 Y84 S97 Y99 N114 T143 K146 W147 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3x14
,
PDBe:3x14
,
PDBj:3x14
PDBsum
3x14
PubMed
25480565
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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