Structure of PDB 3x13 Chain A Binding Site BS01

Receptor Information
>3x13 Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIFKTNTQTDRESLRILRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>3x13 Chain C (length=9) Species: 10377 (Human herpesvirus 4 strain B95-8) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
FLRGRAYGL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3x13 The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
Resolution1.8 Å
Binding residue
(original residue number in PDB)
Y7 D9 F22 F36 Y59 N63 I66 N70 T73 D74 S77 L81 Y84 S97 Y99 Y116 T143 K146 W147 A150 V152 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 D9 F22 F36 Y59 N63 I66 N70 T73 D74 S77 L81 Y84 S97 Y99 Y116 T143 K146 W147 A150 V152 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3x13, PDBe:3x13, PDBj:3x13
PDBsum3x13
PubMed25480565
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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