Structure of PDB 3x12 Chain A Binding Site BS01
Receptor Information
>3x12 Chain A (length=275) Species:
9606
(Homo sapiens) [
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SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPW
IEQEGPEYWDGETRNMKASAQTYRENLRNALRYYNQSEAGSHIIQVMYGC
DVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAR
VAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>3x12 Chain C (length=9) Species:
9606
(Homo sapiens) [
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LSSPVTKSF
Receptor-Ligand Complex Structure
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PDB
3x12
The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
M5 Y7 E63 N66 M67 T73 N77 N80 Y84 I95 Y99 D114 Y123 T143 W147 V152 Q155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
M4 Y6 E62 N65 M66 T72 N76 N79 Y83 I94 Y98 D113 Y122 T142 W146 V151 Q154 L155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3x12
,
PDBe:3x12
,
PDBj:3x12
PDBsum
3x12
PubMed
25480565
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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