Structure of PDB 3wx1 Chain A Binding Site BS01

Receptor Information
>3wx1 Chain A (length=108) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKAS
NLNLIGRPSTVHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWG
LTRSALLP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3wx1 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3wx1 Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs
Resolution1.93 Å
Binding residue
(original residue number in PDB)		C326 C329 C394 C397
Binding residue
(residue number reindexed from 1)		C7 C10 C75 C78
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3wx1, PDBe:3wx1, PDBj:3wx1
PDBsum3wx1
PubMed25108355
UniProtQ8C7D2|CRBN_MOUSE Protein cereblon (Gene Name=Crbn)

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