Structure of PDB 3wuw Chain A Binding Site BS01

Receptor Information
>3wuw Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDGETRNMKASAQTYRENLRTALRYYNQSEAGSHIIQVMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3wuw Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity
Resolution2.0 Å
Binding residue
(original residue number in PDB)
Y7 E63 N66 M67 T73 N77 Y84 Y99 D114 Y123 T143 K146 W147 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 N66 M67 T73 N77 Y84 Y99 D114 Y123 T143 K146 W147 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3wuw, PDBe:3wuw, PDBj:3wuw
PDBsum3wuw
PubMed24563253
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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