Structure of PDB 3wtw Chain A Binding Site BS01

Receptor Information
>3wtw Chain A (length=118) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVAKGDVPDGTLVTVMAGN
DENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQV
ATYHRAIAITVDGPREPR
Ligand information
Receptor-Ligand Complex Structure
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PDB3wtw A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		R139 R142 T169 V170 D171
Binding residue
(residue number reindexed from 1)		R80 R83 T110 V111 D112
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005524 ATP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3wtw, PDBe:3wtw, PDBj:3wtw
PDBsum3wtw
PubMed25083921
UniProtQ03347|RUNX1_MOUSE Runt-related transcription factor 1 (Gene Name=Runx1)

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