Structure of PDB 3wts Chain A Binding Site BS01

Receptor Information
>3wts Chain A (length=119) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVAKGDVPDGTLVTVMAG
NDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQ
VATYHRAIKITVDGPREPR
Ligand information
Receptor-Ligand Complex Structure
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PDB3wts A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		R139 R142 G143 K167 T169 V170 D171
Binding residue
(residue number reindexed from 1)		R81 R84 G85 K109 T111 V112 D113
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005524 ATP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3wts, PDBe:3wts, PDBj:3wts
PDBsum3wts
PubMed25083921
UniProtQ03347|RUNX1_MOUSE Runt-related transcription factor 1 (Gene Name=Runx1)

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