Structure of PDB 3ws3 Chain A Binding Site BS01
Receptor Information
>3ws3 Chain A (length=266) Species:
10090
(Mus musculus) [
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PHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPW
MEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGC
DLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSG
AAEHYKAYLEGECVEWLHRYLKNGLLRTDSPKAHVTHHPRSEVTLRCWAL
GFYPADITLTWQGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYT
CRVYHEGLPEPLTLRW
Ligand information
>3ws3 Chain E (length=9) Species:
10090
(Mus musculus) [
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YQLENYCGL
Receptor-Ligand Complex Structure
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PDB
3ws3
Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses
Resolution
2.335 Å
Binding residue
(original residue number in PDB)
Y31 E33 Y69 E87 K90 Q94 W97 S101 Y108 Q121 F140 W171 A176 H179 Y180 Y183 E187 W191 Y195
Binding residue
(residue number reindexed from 1)
Y6 E8 Y44 E62 K65 Q69 W72 S76 Y83 Q96 F115 W146 A151 H154 Y155 Y158 E162 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3ws3
,
PDBe:3ws3
,
PDBj:3ws3
PDBsum
3ws3
PubMed
25063871
UniProt
P01899
|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)
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