Structure of PDB 3wov Chain A Binding Site BS01

Receptor Information

>3wov Chain A (length=457) Species: 272844 (Pyrococcus abyssi GE5)

TGWEQVLKWLNENTSKYATATSWWDYGYWIESSHARDRDHILALFLARDG
NVSEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRREYNGDETGRGQV
TTILPLQGSGGIYVNPYAGISVRVVQSNTTSKVTVNVRGRAECSPIYTLL
IPGNKKIPGNGRCSDGSPFPYVLYLAPNFGLITYYKVATSNFIKLAFNIP
ISKYSGFTEKLYSNFVPVYGYGNVIVYEFRPFAIYRIEELINGTWKAVNS
LTPGKHELKLYISAFGRDIRNATLYVYAIGNKTEKIKIGEIEYMNHLNEK
PIIVNVTLPKAEKYRLVLVQKGPVGVLTGPPGEIANPIRIAREGEKGTLS
LKVGVDKDYTADLYLRATFIYLVRKENAAFEPHMDTFFITKLKGGIKLHK
GDNVVTAELNMPNGVISSYKEKLEKEYGDKLIIRGIRVEPVFIAEKEYVM
AEVRASA

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 3wov Chain A Residue 1001

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3wov Crystal structure of the C-terminal globular domain of oligosaccharyltransferase (PaAglB-L, Q9V250_PYRAB, PAB2202) from Pyrococcus abyssi
• Resolution: 3.11 Å
• Binding residue (original residue number in PDB): E557 A767 H799 E802
• Binding residue (residue number reindexed from 1): E54 A264 H296 E299
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number: 2.4.99.21: dolichyl-phosphooligosaccharide-protein glycotransferase.

Gene Ontology

Molecular Function

• GO:0004576 oligosaccharyl transferase activity

Biological Process

• GO:0006486 protein glycosylation

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:3wov, PDBe:3wov, PDBj:3wov
• PDBsum: 3wov
• UniProt: Q9V250