Structure of PDB 3wne Chain A Binding Site BS01
Receptor Information
>3wne Chain A (length=138) Species:
11698
(Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)) [
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SSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLA
GRWPVKTVHTDNGSNFTGATVRAACDWAGIKQESMNKELKKIIGQVRDQA
EHLKTAVQMAVFIHNHKRKGGGYSAGERIVDIIATDIQ
Ligand information
>3wne Chain C (length=6) [
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PKIDNG
Receptor-Ligand Complex Structure
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PDB
3wne
Hexapeptide mimetics of LEDGF in complex with HIV-1 integrase
Resolution
1.7 Å
Binding residue
(original residue number in PDB)
D167 Q168 A169 E170 H171 T174
Binding residue
(residue number reindexed from 1)
D98 Q99 A100 E101 H102 T105
Enzymatic activity
Enzyme Commision number
2.7.7.-
2.7.7.49
: RNA-directed DNA polymerase.
2.7.7.7
: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2
: exoribonuclease H.
3.1.26.13
: retroviral ribonuclease H.
3.4.23.16
: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
Biological Process
GO:0015074
DNA integration
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Molecular Function
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Biological Process
External links
PDB
RCSB:3wne
,
PDBe:3wne
,
PDBj:3wne
PDBsum
3wne
PubMed
UniProt
P12497
|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)
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