Structure of PDB 3wn7 Chain A Binding Site BS01

Receptor Information
>3wn7 Chain A (length=286) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGL
LYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDG
HIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLY
AVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAG
GYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYD
GHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVT
Ligand information
>3wn7 Chain B (length=24) Species: 10090 (Mus musculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MDLIDILWRQDIDLGVSREVFDFS
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3wn7 Kinetic, thermodynamic, and structural characterizations of the association between Nrf2-DLGex degron and Keap1
Resolution1.57 Å
Binding residue
(original residue number in PDB)		Y334 R380 N382 G386 N387 R415 S431 G433 H436 I461 R483 Y525 S555 A556 Y572 F577 S602
Binding residue
(residue number reindexed from 1)		Y11 R57 N59 G63 N64 R92 S108 G110 H113 I138 R160 Y202 S232 A233 Y249 F254 S279
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3wn7, PDBe:3wn7, PDBj:3wn7
PDBsum3wn7
PubMed24366543
UniProtQ9Z2X8|KEAP1_MOUSE Kelch-like ECH-associated protein 1 (Gene Name=Keap1)

[Back to BioLiP]