Structure of PDB 3wmg Chain A Binding Site BS01

Receptor Information
>3wmg Chain A (length=589) Species: 45157 (Cyanidioschyzon merolae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TGVTARRIFALAWSSSATMIVIGFIASILEGATLPAFAIVFGRMFQVFTK
SKSQIEGETWKYSVGFVGIGVFEFIVAGSRTALFGIASERLARDLRVAAF
SNLVEQDVTYFDRRKAGELGGKLNNDVQVIQYSFSKLGAVLFNLAQCVVG
IIVAFIFAPALTGVLIALSPLVVLAVVVQMIEMSGNTKRSSEAYASAGSV
AAEVFSNIRTTKAFEAERYETQRYGSKLDPLYRLGRRRYISDGLFFGLSM
LVIFCVYALALWWGGQLIARGSLNLGNLLTAFFSAILGFMGVGQAAQVWP
DVTRGLGAGGELFAMIDRVPQYRRPDPGAEVVTQPLVLKQGIVFENVHFR
YPTRMNVEVLRGISLTIPNGKTVAIVGGSGAGKSTIIQLLMRFYDIEPQG
GGLLLFDGTPAWNYDFHALRSQIGLVSQEPVLFSGTIRDNILYGKRDATD
EEVIQALREANAYSFVMALPDGLDTEVGERGLALSGGQKQRIAIARAILK
HPTLLCLDESTSALDAESEALVQEALDRMMASDGVTSVVIAHRLSTVARA
DLILVMQDGVVVEQGNHSELMALGPSGFYYQLVEKQLAS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3wmg Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		R144 K162 Y163 N378
Binding residue
(residue number reindexed from 1)		R43 K61 Y62 N277
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3wmg, PDBe:3wmg, PDBj:3wmg
PDBsum3wmg
PubMed24591620
UniProtM1VAN7

[Back to BioLiP]