Structure of PDB 3wbn Chain A Binding Site BS01

Receptor Information
>3wbn Chain A (length=450) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADGIWVSGLGPESLA
AVGLFFPVFMGIIALAAGLGVGTSSAIARRIGARDKEGADNVAVHSLILS
LILGVTITITMLPAIDSLFRSMGAKGEAVELAIEYARVLLAGAFIIVFNN
VGNGILRGEGDANRAMLAMVLGSGLNIVLDPIFIYTLGFGVVGAAYATLL
SMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILKDILRVGLPSSLSQL
SMSIAMFFLNSVAITAGGENGVAVFTSAWRITMLGIVPILGMAAATTSVT
GAAYGERNVEKLETAYLYAIKIAFMIELAVVAFIMLFAPQVAYLFTYSES
AQVIKGDLISALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTIFRTL
VMQVGFAYIFVHYTTLGLRGVWIGIVIGNMVAAIVGFLWGRMRISALKKT
Ligand information
Receptor-Ligand Complex Structure
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PDB3wbn Structural basis for the drug extrusion mechanism by a MATE multidrug transporter.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		P50 L53 A54 G57 L58 P61 M126 F261 F262 N264 S265
Binding residue
(residue number reindexed from 1)		P46 L49 A50 G53 L54 P57 M122 F257 F258 N260 S261
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015297 antiporter activity
GO:0042910 xenobiotic transmembrane transporter activity
Biological Process
GO:0042908 xenobiotic transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3wbn, PDBe:3wbn, PDBj:3wbn
PDBsum3wbn
PubMed23535598
UniProtQ8U2X0

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