Structure of PDB 3w3c Chain A Binding Site BS01

Receptor Information
>3w3c Chain A (length=116) Species: 42897 (Shigella flexneri 2a) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EHSIRELGIGLNFLKVSGMSYKDIAKKENLSRAKVTRAFQAASVPQEIIS
LFPIASELNFNDYKILFNYYKGLEKANESLSSTLPILKEEIKDLDTNLPP
DIYKKEILNIIKKSKN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3w3c Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Resolution2.431 Å
Binding residue
(original residue number in PDB)
S150 Y151 K152 R162 T166
Binding residue
(residue number reindexed from 1)
S20 Y21 K22 R32 T36
Binding affinityPDBbind-CN: Kd=16nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3w3c, PDBe:3w3c, PDBj:3w3c
PDBsum3w3c
PubMed23985969
UniProtP0A247|VIRB_SHIFL Virulence regulon transcriptional activator VirB (Gene Name=virB)

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