Structure of PDB 3w2w Chain A Binding Site BS01

Receptor Information
>3w2w Chain A (length=618) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFG
PEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIE
EEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREY
FTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIA
IYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHD
NLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWR
KIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGDEEKVKEV
VDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLYSTPQVHVAISQA
LANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKS
FELLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGL
LKRSGSYYISLVGWELIRVFYNSELRKKLLEEGVGKRFIYHVLREVDTWP
KVGIDEMLKFEVIRHIRGRNKEETKELREKIYGEIKDLLEHVRGNNEVEK
VRGLFTFLKIITDAEVFP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3w2w Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3w2w Crystal Structure of the Cmr2-Cmr3 Subcomplex in the CRISPR-Cas RNA Silencing Effector Complex.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		C448 C451 C478 C481
Binding residue
(residue number reindexed from 1)		C233 C236 C263 C266
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) F264 I270
Catalytic site (residue number reindexed from 1) F49 I55
Enzyme Commision number ?
External links
PDB RCSB:3w2w, PDBe:3w2w, PDBj:3w2w
PDBsum3w2w
PubMed23583914
UniProtQ8U1S6|CMR2_PYRFU CRISPR system Cmr subunit Cmr2 (Gene Name=cmr2)

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