Structure of PDB 3w15 Chain A Binding Site BS01

Receptor Information
>3w15 Chain A (length=336) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLRYHMQGFSGYGVQYSPFFDNRLAVAAGSNFGLVGNGKLFILEIDRSGR
IVEVNSFLTQDCLFDLAWNESHENQVLVAQGDGTLRLFDTTFKEFPIAIF
KEHEREVFSCNWNLVNRQNFLSSSWDGSIKIWSPLRKQSLMTLTPRPLEI
TKMVDPLNAIILKNCVYQAQFSPHDQNLVLSCSGNSYASLFDIRLPSGKN
QNNFLVHSGLEALTCDFNKYRPYVVATGGVDNAIRIWDIRMSCINEIPNA
HGLAIRKVTWSPHHSNILMSASYDMTCRIWRDLSNKTNSTDATKGSIFNF
TQHSEFVFGADWSLWGKPGYVASTAWDGNLFVWNGL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3w15 Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3w15 Crystal structure of peroxisomal targeting signal-2 bound to its receptor complex Pex7p-Pex21p
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D65 L66 C110 N111
Binding residue
(residue number reindexed from 1)		D65 L66 C110 N111
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005053 peroxisome matrix targeting signal-2 binding
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0016558 protein import into peroxisome matrix
GO:0016560 protein import into peroxisome matrix, docking
GO:0072663 establishment of protein localization to peroxisome
Cellular Component
GO:0005737 cytoplasm
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005782 peroxisomal matrix
GO:0005829 cytosol
GO:0062137 cargo receptor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3w15, PDBe:3w15, PDBj:3w15
PDBsum3w15
PubMed23812376
UniProtP39108|PEX7_YEAST Peroxisomal targeting signal 2 receptor (Gene Name=PEX7)

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