Structure of PDB 3vy6 Chain A Binding Site BS01

Receptor Information
>3vy6 Chain A (length=138) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSSSYSGEYGSGGGKRFSHSGNQLDGPITALRVRVNTYYIVGLQVRYGKV
WSDYVGGRNGDLEEIFLHPGESVIQVSGKYKWYLKKLVFVTDKGRYLSFG
KDSGTSFNAVPLHPNTVLRFISGRSGSLIDAIGLHWDV
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain3vy6 Chain B Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3vy6 Structural Basis for Multiple Sugar Recognition of Jacalin-related Human ZG16p Lectin
Resolution2.0 Å
Binding residue
(original residue number in PDB)		G35 Y104 G147 S148 L149 D151
Binding residue
(residue number reindexed from 1)		G14 Y83 G126 S127 L128 D130
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030246 carbohydrate binding
GO:0042834 peptidoglycan binding
Biological Process
GO:0015031 protein transport
GO:0050830 defense response to Gram-positive bacterium
GO:0052373 suppression of symbiont entry into host
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0005796 Golgi lumen
GO:0031410 cytoplasmic vesicle
GO:0042589 zymogen granule membrane
GO:0062023 collagen-containing extracellular matrix
GO:0070701 mucus layer

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3vy6, PDBe:3vy6, PDBj:3vy6
PDBsum3vy6
PubMed24790092
UniProtO60844|ZG16_HUMAN Zymogen granule membrane protein 16 (Gene Name=ZG16)

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