Structure of PDB 3vvs Chain A Binding Site BS01

Receptor Information
>3vvs Chain A (length=444) Species: 2261 (Pyrococcus furiosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADGIWVSGLGPESL
AAVGLFFPVFMGIIALAAGLGVGTSSAIARRIGARDKEGADNVAVHSLIL
SLILGVTITITMLPAIDSLFRSMGAKGEAVELAIEYARVLLAGAFIIVFN
NVGNGILRGEGDANRAMLAMVLGSGLNIVLDPIFIYTLGFGVVGAAYATL
LSMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILKDILRVGLPSSLSQ
LSMSIAMFFLNSVAITAGGENGVAVFTSAWRITMLGIVPILGMAAATTSV
TGAAYGERNVEKLETAYLYAIKIAFMIELAVVAFIMLFAPQVAYLFTIKG
DLISALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTIFRTLVMQVGF
AYIFVHYTTLGLRGVWIGIVIGNMVAAIVGFLWGRMRISALKKT
Ligand information
Receptor-Ligand Complex Structure
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PDB3vvs Structural basis for the drug extrusion mechanism by a MATE multidrug transporter.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		Q34 Y37 N38 F60 F63 M64 I67 N153 N154 N157 M173 Q253 M256
Binding residue
(residue number reindexed from 1)		Q31 Y34 N35 F57 F60 M61 I64 N150 N151 N154 M170 Q250 M253
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015297 antiporter activity
GO:0042910 xenobiotic transmembrane transporter activity
Biological Process
GO:0042908 xenobiotic transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3vvs, PDBe:3vvs, PDBj:3vvs
PDBsum3vvs
PubMed23535598
UniProtQ8U2X0

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