Structure of PDB 3vtb Chain A Binding Site BS01

Receptor Information

>3vtb Chain A (length=240) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLV
SYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDM
SWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLM
AICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMI
QKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN

Ligand information

>3vtb Chain B (length=11) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

KNHPMLMNLLK

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3vtb Combination of Triple Bond and Adamantane Ring on the Vitamin D Side Chain Produced Partial Agonists for Vitamin D Receptor.
Resolution	2.0 Å
Binding residue (original residue number in PDB)	I238 K242 I256 L259 K260 P412 E416
Binding residue (residue number reindexed from 1)	I58 K62 I76 L79 K80 P232 E236

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004879	nuclear receptor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

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Molecular Function

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Biological Process

External links

PDB	RCSB:3vtb, PDBe:3vtb, PDBj:3vtb
PDBsum	3vtb
PubMed	24773565
UniProt	P13053\|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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