Structure of PDB 3vt8 Chain A Binding Site BS01

Receptor Information
>3vt8 Chain A (length=233) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLV
SYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDSQ
DYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSP
DRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLR
SLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN
Ligand information
Receptor-Ligand Complex Structure
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PDB3vt8 Crystal structures of hereditary vitamin D-resistant rickets-associated vitamin D receptor mutants R270L and W282R bound to 1,25-dihydroxyvitamin D3 and synthetic ligands.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		I238 K242 S252 Q255 I256 L259 K260 P412 E416
Binding residue
(residue number reindexed from 1)		I58 K62 S72 Q75 I76 L79 K80 P225 E229
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3vt8, PDBe:3vt8, PDBj:3vt8
PDBsum3vt8
PubMed23944708
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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