Structure of PDB 3v71 Chain A Binding Site BS01

Receptor Information
>3v71 Chain A (length=364) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ISLEDVLLNGQLIDFAIDPSGVKFLEANYPLDSEDQIRKAVFEKFTESTT
LFVGLCHSRNGNFIVQKLVELATPAEQRELLRQMIDGGLLAMCKDKFACR
VVQLALQKFDHSNVFQLIQELSTFDLAAMCTDQISIHVIQRVVKQLPVDM
WTFFVHFLSSGDSLMAVCQDKYGCRLVQQVIDRLAENPKLPCFKFRIQLL
HSLMTCIVRNCYRLSSNEFANYVIQYVIKSSGIMEMYRDTIIDKCLLRNL
LSMSQDKYASHVIEGAFLFAPPALLHEMMEEIFSVKDVESNRDALDILLF
HQYGNYVVQQMISICTAALIELPPAILLLYSGWYEKMKQRVLQHASRLER
FSSGKKIIDSVMRH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3v71 Divergence of PUF protein specificity through variations in an RNA-binding pocket
Resolution2.902 Å
Binding residue
(original residue number in PDB)
Q214 K252 Y253 R256 Q259 F300 N302 Y303 Q306 K338 S341 H342 E345 F383 Q385 N388 Y389 Q392 F439 S440 S441 K444
Binding residue
(residue number reindexed from 1)
Q133 K171 Y172 R175 Q178 F219 N221 Y222 Q225 K257 S260 H261 E264 F300 Q302 N305 Y306 Q309 F351 S352 S353 K356
Binding affinityPDBbind-CN: Kd=7.4nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3v71, PDBe:3v71, PDBj:3v71
PDBsum3v71
PubMed
UniProtO44169|PUF7_CAEEL Pumilio domain-containing protein 7 (Gene Name=puf-7)

[Back to BioLiP]