Structure of PDB 3v71 Chain A Binding Site BS01
Receptor Information
>3v71 Chain A (length=364) Species:
6239
(Caenorhabditis elegans) [
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ISLEDVLLNGQLIDFAIDPSGVKFLEANYPLDSEDQIRKAVFEKFTESTT
LFVGLCHSRNGNFIVQKLVELATPAEQRELLRQMIDGGLLAMCKDKFACR
VVQLALQKFDHSNVFQLIQELSTFDLAAMCTDQISIHVIQRVVKQLPVDM
WTFFVHFLSSGDSLMAVCQDKYGCRLVQQVIDRLAENPKLPCFKFRIQLL
HSLMTCIVRNCYRLSSNEFANYVIQYVIKSSGIMEMYRDTIIDKCLLRNL
LSMSQDKYASHVIEGAFLFAPPALLHEMMEEIFSVKDVESNRDALDILLF
HQYGNYVVQQMISICTAALIELPPAILLLYSGWYEKMKQRVLQHASRLER
FSSGKKIIDSVMRH
Ligand information
>3v71 Chain B (length=7) [
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cuguauc
.......
Receptor-Ligand Complex Structure
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PDB
3v71
Divergence of PUF protein specificity through variations in an RNA-binding pocket
Resolution
2.902 Å
Binding residue
(original residue number in PDB)
Q214 K252 Y253 R256 Q259 F300 N302 Y303 Q306 K338 S341 H342 E345 F383 Q385 N388 Y389 Q392 F439 S440 S441 K444
Binding residue
(residue number reindexed from 1)
Q133 K171 Y172 R175 Q178 F219 N221 Y222 Q225 K257 S260 H261 E264 F300 Q302 N305 Y306 Q309 F351 S352 S353 K356
Binding affinity
PDBbind-CN
: Kd=7.4nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
View graph for
Molecular Function
External links
PDB
RCSB:3v71
,
PDBe:3v71
,
PDBj:3v71
PDBsum
3v71
PubMed
UniProt
O44169
|PUF7_CAEEL Pumilio domain-containing protein 7 (Gene Name=puf-7)
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