Structure of PDB 3v6y Chain A Binding Site BS01

Receptor Information
>3v6y Chain A (length=393) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLPTWSLDSNGEMRSRLSLSEVLDSGDLMKFAVDKTGCQFLEKAVKGSLT
SYQKFQLFEQVIGRKDDFLKLSTNIFGNYLVQSVIGISLATNDDGYTKRQ
EKLKNFISSQMTDMCLDKFACRVIQSSLQNMDLSLACKLVQALPRDARLI
AICVDQNANHVIQKVVAVIPLKNWEFIVDFVATPEHLRQICSDKYGCRVV
QTIIEKLTADSMNVDLTSAAQNLRERALQRLMTSVTNRCQELATNEYANY
IIQHIVSNDDLAVYRECIIEKCLMRNLLSLSQEKFASHVVEKAFLHAPLE
LLAEMMDEIFDGYDALDIMMFHQFGNYVVQCMLTICCDAVSGRRQTKEGG
YDHAISFQDWLKKLHSRVTKERHRLSRFSSGKKMIETLANLRS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3v6y Divergence of PUF protein specificity through variations in an RNA-binding pocket
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K201 E208 N244 Y245 R288 Q291 H326 K360 Y361 R364 N415 Y416 Q419 K450 S453 H454 E457 F495 N500 Y501 Q504 F552 S553 S554 K557
Binding residue
(residue number reindexed from 1)		K35 E42 N78 Y79 R122 Q125 H160 K194 Y195 R198 N249 Y250 Q253 K284 S287 H288 E291 F321 N326 Y327 Q330 F378 S379 S380 K383
Binding affinityPDBbind-CN: Kd=3.9nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3v6y, PDBe:3v6y, PDBj:3v6y
PDBsum3v6y
PubMed
UniProtQ09312|FBF2_CAEEL Fem-3 mRNA-binding factor 2 (Gene Name=fbf-2)

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