Structure of PDB 3v5x Chain A Binding Site BS01

Receptor Information
>3v5x Chain A (length=151) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFKE
FKMHEQIENEYIIGLLQQRSQYNVHKLSEMLSLFEKGLKNVKNEYEQLNY
AKQLKERLEAFTRDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQH
C
Ligand information
Ligand IDFEO
InChIInChI=1S/2Fe.O
InChIKeyNPMYUMBHPJGBFA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Fe]O[Fe]
OpenEye OEToolkits 1.5.0O([Fe])[Fe]
FormulaFe2 O
NameMU-OXO-DIIRON
ChEMBL
DrugBank
ZINC
PDB chain3v5x Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3v5x Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5).
Resolution1.85 Å
Binding residue
(original residue number in PDB)		H15 H57 E58 E61 H80 H126 E130
Binding residue
(residue number reindexed from 1)		H12 H54 E55 E58 H75 H118 E122
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006879 intracellular iron ion homeostasis

View graph for
Biological Process
External links
PDB RCSB:3v5x, PDBe:3v5x, PDBj:3v5x
PDBsum3v5x
PubMed22253436
UniProtQ9UKA1|FBXL5_HUMAN F-box/LRR-repeat protein 5 (Gene Name=FBXL5)

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