Structure of PDB 3v5u Chain A Binding Site BS01

Receptor Information
>3v5u Chain A (length=297) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGT
SLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKN
LQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKN
NPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAF
GTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAE
NVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG
Ligand information
Ligand IDNA
InChIInChI=1S/Na/q+1
InChIKeyFKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Na+]
FormulaNa
NameSODIUM ION
ChEMBL
DrugBankDB14516
ZINC
PDB chain3v5u Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3v5u Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		A47 T50 S51 E213 S236
Binding residue
(residue number reindexed from 1)		A47 T50 S51 E206 S229
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005262 calcium channel activity
GO:0008273 calcium, potassium:sodium antiporter activity
Biological Process
GO:0006874 intracellular calcium ion homeostasis
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3v5u, PDBe:3v5u, PDBj:3v5u
PDBsum3v5u
PubMed22323814
UniProtQ57556|Y091_METJA Uncharacterized membrane protein MJ0091 (Gene Name=MJ0091)

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