Structure of PDB 3v43 Chain A Binding Site BS01
Receptor Information
>3v43 Chain A (length=112) Species:
9606
(Homo sapiens) [
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HMEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVR
VKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMP
KGMWICQICRPR
Ligand information
>3v43 Chain Q (length=7) Species:
9606
(Homo sapiens) [
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ARTKQTA
Receptor-Ligand Complex Structure
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PDB
3v43
Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription
Resolution
1.47 Å
Binding residue
(original residue number in PDB)
I260 A275 N277 M278 L279 F280 C281 D282 D285 M300 P301 G303
Binding residue
(residue number reindexed from 1)
I59 A74 N76 M77 L78 F79 C80 D81 D84 M99 P100 G102
Enzymatic activity
Enzyme Commision number
2.3.1.48
: histone acetyltransferase.
External links
PDB
RCSB:3v43
,
PDBe:3v43
,
PDBj:3v43
PDBsum
3v43
PubMed
22713874
UniProt
Q92794
|KAT6A_HUMAN Histone acetyltransferase KAT6A (Gene Name=KAT6A)
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