Structure of PDB 3uvy Chain A Binding Site BS01

Receptor Information
>3uvy Chain A (length=109) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMG
TIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFL
QKINELPTE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3uvy Histone recognition and large-scale structural analysis of the human bromodomain family.
Resolution2.02 Å
Binding residue
(original residue number in PDB)
W81 V87 L92 L94 Y139 N140 K141 D144 D145 I146 M149
Binding residue
(residue number reindexed from 1)
W23 V29 L34 L36 Y81 N82 K83 D86 D87 I88 M91
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3uvy, PDBe:3uvy, PDBj:3uvy
PDBsum3uvy
PubMed22464331
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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