Structure of PDB 3uvx Chain A Binding Site BS01

Receptor Information
>3uvx Chain A (length=127) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTEE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3uvx Histone recognition and large-scale structural analysis of the human bromodomain family.
Resolution1.91 Å
Binding residue
(original residue number in PDB)
W81 L94 Y139 N140 K141 D144 D145
Binding residue
(residue number reindexed from 1)
W40 L53 Y98 N99 K100 D103 D104
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3uvx, PDBe:3uvx, PDBj:3uvx
PDBsum3uvx
PubMed22464331
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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