Structure of PDB 3uri Chain A Binding Site BS01

Receptor Information
>3uri Chain A (length=328) Species: 5116 (Cryphonectria parasitica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTA
SEVQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVT
GQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASL
DSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGY
AVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYV
FPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGI
NIFGDVALKAAFVVFNGATTPTLGFASK
Ligand information
Receptor-Ligand Complex Structure
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PDB3uri An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D15 D33 D35 G37 Y78 G79 D80 F193 D218 G220 T221 T222 L223
Binding residue
(residue number reindexed from 1)		D15 D33 D35 G37 Y77 G78 D79 F192 D217 G219 T220 T221 L222
Enzymatic activity
Catalytic site (original residue number in PDB) D35 S38 D40 W42 G79 T219 T222
Catalytic site (residue number reindexed from 1) D35 S38 D40 W42 G78 T218 T221
Enzyme Commision number 3.4.23.22: endothiapepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3uri, PDBe:3uri, PDBj:3uri
PDBsum3uri
PubMed22525752
UniProtP11838|CARP_CRYPA Endothiapepsin (Gene Name=EAPA)

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