Structure of PDB 3upr Chain A Binding Site BS01
Receptor Information
>3upr Chain A (length=275) Species:
9606
(Homo sapiens) [
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SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPW
IEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGC
DVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAR
VAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>3upr Chain P (length=9) [
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HSITYLLPV
Receptor-Ligand Complex Structure
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PDB
3upr
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Resolution
1.999 Å
Binding residue
(original residue number in PDB)
Y7 Y59 E63 N66 M67 A69 T73 N77 Y84 Y99 T143 W147 V152 Q155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 Y58 E62 N65 M66 A68 T72 N76 Y83 Y98 T142 W146 V151 Q154 L155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3upr
,
PDBe:3upr
,
PDBj:3upr
PDBsum
3upr
PubMed
22645359
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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