Structure of PDB 3um3 Chain A Binding Site BS01

Receptor Information
>3um3 Chain A (length=377) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTHWFHRNPLKATAPVSFNYYGVVTGPSASKICNDLRSSRARLLELFTDL
SCNPEMMKNAADSYFSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQV
PSAQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIA
AGIFKHLKESHLPKLITPAEKGRDLESRLIEAYVIQCQAEAQEVTIARAI
ELKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRKYLHLKMCFYT
AYAYCYHGETLLASDKCGEAIRSLQEAEKLYAKAEALCKEYGETKGPGPT
VKPSGHLFFRKLGNLVKNTLEKCQRENGFIYFQKIPTEAPQLELKANYGL
VEPIPFEFPPTSVQWTPETLAAFDLTK
Ligand information
Receptor-Ligand Complex Structure
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PDB3um3 Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		K141 H144 R145 T195 R198 L202 H204 L208 L350
Binding residue
(residue number reindexed from 1)		K141 H144 R145 T195 R198 L202 H204 L208 L350
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0007084 mitotic nuclear membrane reassembly
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3um3, PDBe:3um3, PDBj:3um3
PDBsum3um3
PubMed22484091
UniProtQ5VW32|BROX_HUMAN BRO1 domain-containing protein BROX (Gene Name=BROX)

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