Structure of PDB 3ugp Chain A Binding Site BS01

Receptor Information
>3ugp Chain A (length=179) Species: 271 (Thermus aquaticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELI
REVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIA
REGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKF
EYKRRFKFSTYATWWIRQAINRAIADQAR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ugp Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit.
Resolution2.697 Å
Binding residue
(original residue number in PDB)
L108 N206 R208 L209 S212 K215 K241 F242 E243 R246 F248 K249 S251 T252 Y253 T255 W256 W257
Binding residue
(residue number reindexed from 1)
L16 N114 R116 L117 S120 K123 K149 F150 E151 R154 F156 K157 S159 T160 Y161 T163 W164 W165
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:3ugp, PDBe:3ugp, PDBj:3ugp
PDBsum3ugp
PubMed22136875
UniProtQ9EZJ8|SIGA_THEAQ RNA polymerase sigma factor SigA (Gene Name=sigA)

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