Structure of PDB 3ueo Chain A Binding Site BS01

Receptor Information
>3ueo Chain A (length=186) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLFSQKSFLVLGFSNENESNIANIIKENAGKIMTVADYAVVPLLGCEVEA
TVGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQ
CAGAEKESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKY
EAAKKWNLPAVTIAWLLETARTGKRADESHFLIENS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ueo Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
G702 K704
Binding residue
(residue number reindexed from 1)
G147 K149
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3ueo, PDBe:3ueo, PDBj:3ueo
PDBsum3ueo
PubMed23891287
UniProtQ92547|TOPB1_HUMAN DNA topoisomerase 2-binding protein 1 (Gene Name=TOPBP1)

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