Structure of PDB 3u04 Chain A Binding Site BS01

Receptor Information
>3u04 Chain A (length=172) Species: 205920 (Ehrlichia chaffeensis str. Arkansas) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSVLSIVTVPDKRLSLCSEEVEKVDQSIRKLVDDMFETMHANQGLGLAAV
QVGVHKRILVMNVPEEIEGYELYGGPYCIINPKIVDISQEKVKLKEGCLS
VPGYFDYIVRPQRIAVQYLDYNGNECIIKAQGWLARCLQHEIDHLNGTVF
LKYLSKFKRDFAIEKVKKKERT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3u04 Chain A Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3u04 Crystal structure of peptide deformylase from ehrlichia chaffeensis in complex with actinonin
Resolution1.7 Å
Binding residue
(original residue number in PDB)		C111 H153 H157
Binding residue
(residue number reindexed from 1)		C98 H140 H144
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G46 Q51 C111 L112 H153 E154 H157
Catalytic site (residue number reindexed from 1) G46 Q51 C98 L99 H140 E141 H144
Enzyme Commision number 3.5.1.88: peptide deformylase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0018206 peptidyl-methionine modification

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Molecular Function
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Biological Process
External links
PDB RCSB:3u04, PDBe:3u04, PDBj:3u04
PDBsum3u04
PubMed
UniProtQ2GI30

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