Structure of PDB 3tsz Chain A Binding Site BS01
Receptor Information
>3tsz Chain A (length=341) Species:
9606
(Homo sapiens) [
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SMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRV
NNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFY
IRTHFEYEKESPYGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVE
RGIIPNKNRAEQLASVQYTKFPAYERVVLREAGFLRPVTIFGPIADVARE
KLAREEPDIYQIAKSEPRDAGTDQRGIIRLHTIKQIIDQDKHALLDVTPN
AVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKL
RKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWVSE
Ligand information
>3tsz Chain B (length=10) Species:
9606
(Homo sapiens) [
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EFKQTSSFLV
Receptor-Ligand Complex Structure
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PDB
3tsz
The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1.
Resolution
2.502 Å
Binding residue
(original residue number in PDB)
S432 V433 G434 L435 L437 G439 A448 R480 V484 L487 L488 D514 Y550 N551 G552 L558 R571
Binding residue
(residue number reindexed from 1)
S12 V13 G14 L15 L17 G19 A28 R60 V64 L67 L68 D94 Y130 N131 G132 L138 R151
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3tsz
,
PDBe:3tsz
,
PDBj:3tsz
PDBsum
3tsz
PubMed
22030391
UniProt
Q07157
|ZO1_HUMAN Tight junction protein ZO-1 (Gene Name=TJP1)
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