Structure of PDB 3tso Chain A Binding Site BS01

Receptor Information
>3tso Chain A (length=169) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTA
AVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKE
LYDHAEATIVVMLVGNKSDLSQAREVPTEEARMFAENNGLLFLETSALDS
TNVELAFETVLKEIFAKVS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3tso Chain A Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3tso Structure of the cancer associated Rab25 protein in complex with FIP2
Resolution1.8 Å
Binding residue
(original residue number in PDB)		T26 T44
Binding residue
(residue number reindexed from 1)		T17 T35
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:3tso, PDBe:3tso, PDBj:3tso
PDBsum3tso
PubMed
UniProtP57735|RAB25_HUMAN Ras-related protein Rab-25 (Gene Name=RAB25)

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