Structure of PDB 3ts0 Chain A Binding Site BS01

Receptor Information
>3ts0 Chain A (length=136) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGF
RSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGGDRCYNCG
GLDHHAKECKLPPQPKKCHFCQSINHMVASCPLKAQ
Ligand information
>3ts0 Chain U (length=23) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggguagugauuuuacccuggag
<<<<<<.......>>>>>>....
Receptor-Ligand Complex Structure
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PDB3ts0 Molecular Basis for Interaction of let-7 MicroRNAs with Lin28.
Resolution2.763 Å
Binding residue
(original residue number in PDB)		K45 W46 F47 N48 V49 R50 M51 F53 F55 D71 F73 H75 Q76 F84 R85 E89 S100 K102 E105
Binding residue
(residue number reindexed from 1)		K11 W12 F13 N14 V15 R16 M17 F19 F21 D37 F39 H41 Q42 F50 R51 E55 S66 K68 E71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:3ts0, PDBe:3ts0, PDBj:3ts0
PDBsum3ts0
PubMed22078496
UniProtQ8K3Y3|LN28A_MOUSE Protein lin-28 homolog A (Gene Name=Lin28a)

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