Structure of PDB 3tr8 Chain A Binding Site BS01

Receptor Information
>3tr8 Chain A (length=184) Species: 777 (Coxiella burnetii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNAMDFSDDNLIWLDLEMTGLDPERDRIIEIATIVTNSHLDILAEGPAFA
IHQPDKLLTAMDNWNTSHHTASGLLERVKNSSVDEVEAETLTLAFLEKYV
SAGKSPLCGNSVCQDRRFLSRYMPRLNQFFHYRHLDVTTLKILAQRWAPQ
IAAAHIKESQHLALQDIRDSIEELRYYRAHLLNL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain3tr8 Chain A Residue 184 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3tr8 Structural genomics for drug design against the pathogen Coxiella burnetii.
Resolution2.503 Å
Binding residue
(original residue number in PDB)		D12 E14 D163
Binding residue
(residue number reindexed from 1)		D15 E17 D166
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.15.-
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters
Biological Process
GO:0006259 DNA metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3tr8, PDBe:3tr8, PDBj:3tr8
PDBsum3tr8
PubMed26033498
UniProtQ83C93|ORN_COXBU Oligoribonuclease (Gene Name=orn)

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